Medical imaging techniques such as ultrasound, X-ray, computed tomography (CT), and magnetic resonance imaging (MRI) are integral screening modalities in medicine due to their ability to non-invasively visualise internal organs. Elastography is an emerging imaging […]
The placenta nourishes the fetus and removes its waste products in pregnancy. Fundamental to its function is the healthy development of an extensively branched tree-like structure known as the vascular tree. In pathological pregnancies, abnormalities […]
In our group, we are developing in silico models and numerical techniques for understanding the mechanisms of established and novel therapeutic strategies against cancers. The complex nature of solid tumours, tendency for mutation, and ability […]
In medical imaging, image registration is the process of transforming different sets of data into one coordinate system, i.e. projecting images into a common reference framework. Clinical data could include magnetic resonance imaging (MRI) scans, […]
Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is characterized at the molecular level by the accumulation of two specific protein-based pathologies within the brain: amyloid plaques composed of extracellular amyloid-β peptide (Aβ), intracellular […]
Pulmonary fibrosis is a respiratory disease in which scar tissue is formed in the lung that may lead to functional lung volume loss, breathlessness and eventually potentially death. Radiation-induced fibrosis can occur within the lungs […]
Brain metastases, or secondary brain tumours, occur in 10% to 30% of adults with cancer. Treatment for people who developed brain cancer metastasis is often surgery, radiation therapy or both. Clinical evidence suggests however that […]
A major event in cancer progression is angiogenesis, the formation of new blood vessels from the existing vasculature, which provide a means for supplying nutrients and oxygen to a starving growing tumour. Thus, in order […]
Collagen scaffold materials are being investigated for their advantageous features in tissue engineering and regenerative medicine. To date, porous collagen sponges have been used to support in vitro growth of many types of tissues, including […]
The nematode Caenorhabditis elegans (C.elegans) has emerged as a powerful model-organism for the study of many different physiological processes. For example the C.elegans has been used extensively to investigate the neuronal and behavioural response and […]
